Dr. Rhonda Patrick on Instagram: "Nicotine can enhance cognition, but it comes at a cost to cardiovascular health. A single 2–4 mg nicotine pouch can raise blood pressure by ~5 mmHg and increase resting heart rate by ~5–10 beats per minute. Higher doses lead to more pronounced elevations. More concerning is nicotine’s effect on arterial stiffness, which is a marker strongly associated with long-term cardiovascular disease risk. These effects are driven largely by nicotine’s activation of the sym