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Top suggestions for pI3K pathway
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4:44
YouTube
Onkoview
The PI3K/AKT signalling pathway
The phoshatidylinositol-3 kinase (PI3K) can be activated by binding directly or via the protein IRS-1 to the activated receptor tyrosine kinase. Alternatively, PI3K can be activated by binding to the GTP-bound form of the membrane bound protein Ras. Active PI3K catalyzes the formation of membrane bound PIP3. The second messenger PIP3 activates ...
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Cancer starts when normal biological signals in the body go haywire, also known as dysregulation. In breast cancer, one of the most common signals that can go haywire is called PI3K, which controls how cells grow and stay healthy. Learn more from our Lead Medical Director, Jennifer Schutzman who uses everyday objects to explain this critical pathway in breast cancer and efforts to target it more precisely than ever before. Learn more and watch the full video series: https://www.gene.com/stories/
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