After sparking the 49ers with a handful of impressive runs, Christian McCaffrey looked like himself early in the game against ...

The Bills sacked Purdy twice, Greg Rousseau getting one while the other was called a team sack because Purdy lost a fumble ...

The Buffalo Bills didn't just beat the San Francisco 49ers on Sunday night. They destroyed the reigning NFC champions. The ...

The Buffalo Bills proved snow can't stop them, which we've seen time and again in Western New York (hey, why are they ...

San Francisco running back Christian McCaffrey suffered a knee injury that coach Kyle Shanahan described as “potentially” ...

The 49ers’ third straight defeat came in 35-10 fashion to the AFC East-clinching Buffalo Bills amid a snowstorm at Highmark ...

The Week 13 Sunday slate closes with the Buffalo Bills (9-2) hosting the San Francisco 49ers (5-6) on Sunday Night Football.

The BetMGM bonus code is FPB50 for NFL betting and it offers an exclusive welcome bonus worth up to $1,550 for the Buffalo ...

The 49ers just lost 35-10 to the Buffalo Bills. Now the 49ers are 5-7 and all alone in last place in the NFL West. Here are ...

A Buffalo Bills fan seemingly tried to use the snowy weather to their advantage on Sunday night as they appeared to toss a ...

The Buffalo Bills dominated the San Francisco 49ers on Sunday night, winning 35-10 in Highmark Stadium in Orchard Park, N.Y.

On a snowy night in Orchard Park, N.Y., the Buffalo Bills clinched the AFC East title with a dominant win over the San ...