The 49ers just lost 35-10 to the Buffalo Bills. Now the 49ers are 5-7 and all alone in last place in the NFL West. Here are ...

Christian McCaffrey is dealing with an injury again. The 49ers running back went down with a knee injury in the second ...

The Bills are a Super Bowl contender and the 49ers somehow probably aren’t even a playoff team. That’s how Sunday night’s ...

San Francisco 49ers quarterback Brock Purdy official game status revealed for Week 13 primetime matchup against the Buffalo ...

The San Francisco 49ers are extremely banged up going into their Week 13 showdown with the Buffalo Bills. However, they will ...

San Francisco 49ers quarterback Brock Purdy is expected to play Sunday night against the Buffalo Bills, according to ESPN's ...

San Francisco 49ers quarterback Brock Purdy missed the team's loss to the Green Bay Packers in Week 12 with a shoulder injury ...

Although Coleman and Kincaid are out, Buffalo will welcome one offensive starter back to the lineup. Right tackle Spencer ...

It's Buffalo Bills vs San Francisco 49ers in Week 13 of the NFL season. Can Josh Allen and company outduel Christian ...

San Francisco's starting quarterback missed last week's loss to the Packers. Here's the latest on whether he'll play in ...

San Francisco 49ers star quarterback Brock Purdy has been given an injury update in time for their Week 13 match up against ...

QB Brock Purdy injured his shoulder in Week 11 against the Seattle Seahawks and wound up missing the team’s blowout Week 12 ...