The Buffalo Bills will look to lock up a playoff spot in their Week 13 showdown with the San Francisco 49ers. Here are five storylines to watch.

You can listen on SiriusXM satellite radio on channel 225 (Bills feed) and channel 226 (49ers feed), and on traditional radio, the Bills Radio Network has stations all across the state. Chris Brown has the play-by-play, Eric Wood is the analyst, and Sal Capaccio is the sideline reporter. The network includes:

It’s Week 13 in the NFL, and the Buffalo Bills are preparing to host the San Francisco 49ers on Sunday Night Football at 8:20 p.m. Buffalo (9-2) enters the contest having won six straight and is coming off a bye week. Meanwhile, San Francisco (5-6) has dropped two straight and three of five as injuries continue to pile up.

A light dusting of snow began covering the Buffalo Bills' facility on Friday as the team completed its final practice of the week inside Highmark Stadium.

ORCHARD PARK - The forecasting models are showing that Sunday night, the fabulous fall we have enjoyed in Western New York could be coming to an end, just in time for the Buffalo Bills to host the San Francisco 49ers at Highmark Stadium.