Kirk Cousins threw four interceptions and tossed the Atlanta Falcons' playoff plans into disarray. Brock Purdy couldn't ...

San Francisco running back Christian McCaffrey suffered a knee injury that coach Kyle Shanahan described as “potentially” ...

The situation for the San Francisco 49ers is so dire that Brock Purdy had to send a clear and forceful message to his ...

Lake-effect snow has been hitting Buffalo throughout the holiday weekend with is expected to continue off and on through ...

The most expensive state to live in is not California or New York, according to 2024 data. Here are the top 10. You’re ...

The weather outside was frightful at Highmark Stadium in Orchard Park, New York on Sunday night, but the way the San ...

The Bills are coming off a bye week and riding a six-game winning streak behind MVP favorite Josh Allen, most recently ...

The San Francisco 49ers suffered another crushing defeat Sunday night, falling 35-10 to the Buffalo Bills. The loss marked ...

Josh Allen scored a receiving touchdown on a pass he threw in his latest do-everything performance, and the Buffalo Bills ...

Before the 2024 NFL season, Sunday night's Week 13 matchup between the Buffalo Bills and San Francisco 49ers might've been ...

Buffalo Bills outside linebacker Greg Rousseau chases down San Francisco 49ers quarterback Brock Purdy to boosts his 2024 NFL ...

Follow along for updates throughout the game as the Buffalo Bills take on the San Francisco 49ers at snowy Highmark Stadium.