Authors explore complexities in scaling gene-therapy production with special attention is to monitoring and enhancing ...

2 Centre for Synthetic Biology and Innovation, Imperial College London, London, UK 3 Centre for Process Systems Engineering, Department of Chemical Engineering, Imperial College London, London, UK ...

Are low gene editing efficiency or gene expression levels preventing your research from advancing? Is your transfection method killing your cells? Are you struggling to reproduce your initial results ...

If you work in a lab, whether you are researching the cutting edge of cell and gene therapy development or running a simple molecular binding screen, the chances are you have done some transfection in ...

Hinnah Campwala (left) is a Principal Scientist in the Cell Biology Development Group at Sartorius BioAnalytical Instruments (Michigan, USA). With a background in drug discovery and immune cell ...

Abstract: The efficient application of the newly developed gene-editing method CRISPR/Cas9 requires more accurate intracellular gene delivery. Traditional delivery approaches, such as lipotransfection ...

1 Translational Research Institute, Henan Provincial People’s Hospital, Henan Key Laboratory of Stem Cell Differentiation and Modification, School of Clinical Medicine, Henan University, Zhengzhou, ...

When to Use Transfection Reagents, Viral Transduction or Electroporation No single delivery method is ideal for all situations, but researchers may routinely employ a suboptimal approach for the sake ...

Viral carrier transport efficiency of gene delivery is high, depending on the type of vector. However, viral delivery poses significant safety concerns such as ...