This study offers important insight into the pathogenic basis of intragenic frameshift deletions in the carboxy-terminal domain of MECP2, which account for some Rett syndrome cases, yet similar ...

For decades, biology has relied on one central assumption: the genetic code is precise. DNA is transcribed into RNA, RNA is ...

A new study finds that at least one Archaea has surprisingly flexibility when interpreting genetic code, which goes against a ...

Gene editing can repair mutations that prematurely halt protein synthesis, resulting in incomplete peptides that cause various diseases. However, other approaches achieve the same effect without ...

Researchers uncovered a microbe that treats one stop codon as both a termination signal and an amino-acid instruction, revealing surprising genetic flexibility that may inspire new ways to influence ...

The beauty of the DNA code is that organisms interpret it unambiguously. Each three-letter nucleotide sequence, or codon, in a gene codes for a unique amino acid that's added to a chain of amino acids ...

To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University led by Chen Peng from College of ...

The E.P.A. under Trump is moving to eliminate credits to carmakers for the fuel-saving start-stop function. By Ben Blatt Would you be willing to pay more for gas if your car could be a little less ...

Yale scientists have reprogrammed the genetic code of an organism, creating a novel genomically recoded organism (GRO) with only one stop codon, enabling the production of synthetic proteins with new ...

Synthetic biologists from Yale were able to re-write the genetic code of an organism - a novel genomically recoded organism (GRO) with one stop codon - using a cellular platform that they developed ...

Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. Notably, a vast variety of naturally occurring noncanonical ...