Researchers have discovered how cells activate a last-resort DNA repair system when severe damage strikes. When genetic ...

CpG density and epigenetic modification state modulate DNA mechanics, altering its intrinsic compatibility with nucleosome formation.

A new study published today in Science Translational Medicine by researchers at The University of Texas MD Anderson Cancer Center details a therapeutic vulnerability in  patients with an aggressive ...

Bacteria use a short RNA guide to detect viruses and activate a self-destruct mechanism that protects the wider microbial ...

Study finds CRISPR/Cas gene editing causes “chromatin fatigue” – another surprise mechanism by which it can produce unwanted ...

Cancer’s most catastrophic DNA damage has long looked like a crime scene without a culprit, with chromosomes shattered and ...

Alcohol consumption leads to the formation of a toxic compound called acetaldehyde, which damages DNA. A research team from ...

The Trump administration has proposed new rules that would require Australians to disclose up to five years of social media history to enter the country. The requirement would also apply to British ...

An international research team has identified a human protein, ANKLE1, as the first DNA-cutting enzyme (nuclease) in mammals capable of detecting and responding to physical tension in DNA. This ...

“By enhancing DNA repair, we can heal tissue damage that occurs during a heart attack,” Ibrahim said. “We are particularly excited because TY1 also works in other conditions, including autoimmune ...

A groundbreaking gene-editing method from UT Austin is changing the game for treating complex genetic diseases like cystic fibrosis, hemophilia, and Tay Sachs. Using retrons—DNA tools borrowed from ...

A new fluorescent sensor is giving scientists an unprecedented view of how cells respond to DNA damage, capturing the repair process as it unfolds in real time. The tool, developed at Utrecht ...