AI-designed protein shows 50% greater anti-inflammatory effect in animal studies

A research team has developed a next-generation anti-inflammatory protein using AI and supercomputing. The team, led by ...
eLife

Translational reading frame determines the pathogenicity of C-terminal frameshift deletions in MeCP2: an alternative therapeutic approach

This study offers important insight into the pathogenic basis of intragenic frameshift deletions in the carboxy-terminal domain of MECP2, which account for some Rett syndrome cases, yet similar ...

Study uncovers how calcium controls insulin quality in the endoplasmic reticulum

Calcium (Ca2+) drives many cellular functions, though the way it controls quality of proteins in the endoplasmic reticulum ...