A new study describes a key molecular mechanism that explains how cells exchange information through extracellular vesicles (EVs), small particles with great therapeutic potential. The results, ...

Cells contain a blueprint in the form of DNA that dictates what they can make. This blueprint is converted into a message, or mRNA, which is then converted into protein. Although DNA remains the same ...

Scientists have discovered that boosting lysosome activity helps cells clear progerin, the toxic protein behind premature aging in progeria, offering a potential new way to fight aging-related ...

The announcement of a landmark deal with a pharmaceutical giant validates Arrowhead's technology. For reference, the TRiM platform is a key part of the investment case for the stock. Arrowhead's ...

Type-II diabetes is a chronic disease caused by insulin resistance due to pancreatic β-cell dysfunction. Mutations in a single gene, HNF1A, which codes for the transcription factor hepatocyte nuclear ...

Apart from carrying the information to encode proteins in, RNA molecules can adopt intricate 2D and 3D structures. Specifically, the same RNA molecule can switch between ON and OFF structures, ...

How does a cell know when it’s been damaged? A molecular alarm, set off by mutated RNA and colliding ribosomes, signals danger. When the sun shines on your skin, what does it hit? When it causes a ...

1 Laboratory of Seeds Molecular Biology, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland 2 University of Warsaw, Faculty of Biology, Institute of Genetics and ...

It’s driven by red blood cells and not the blood clots traditionally associated with this sort of damage. “We’ve discovered a completely new blood-clotting mechanism that has nothing to do with the ...

RNA-based medicines are one of the most promising ways to fight human disease, as demonstrated by the recent successes of RNA vaccines and double-stranded RNA (dsRNA) therapies. But while health care ...