This study offers important insight into the pathogenic basis of intragenic frameshift deletions in the carboxy-terminal domain of MECP2, which account for some Rett syndrome cases, yet similar ...

It has been claimed that because most of our DNA is active, it must be important, but now human-plant hybrid cells have been ...

Three start-ups are aiming to create gene-edited babies. Columnist Michael Le Page has no doubt that editing our offspring ...

Researchers showed that a severe drop in NAD+—a core energy molecule—drives Alzheimer’s pathology in both human brains and mouse models.

Even as humpbacks rebound in number, their genomes reveal a loss of genetic diversity and a buildup of harmful mutations left ...

Given the totality of energy production, nuclear energy is very safe, but when things go wrong, they go very wrong as ...

A major evolutionary theory says most genetic changes don’t really matter, but new evidence suggests that’s not true. Researchers found that helpful mutations happen surprisingly often. The twist is ...

A microscopic flaw in the brain’s cellular scaffolding can shape brain size for life.

Alzheimer’s has long been considered irreversible, but new research challenges that assumption. Scientists discovered that severe drops in the brain’s energy supply help drive the disease—and ...

For over a century, Alzheimer's disease (AD) has been considered irreversible. Consequently, research has focused on disease ...

The analysis revealed that about 2 per cent of sperm from men in their early 30s contained disease-causing mutations. That ...

Scientists have revealed parts of the genome that are especially vulnerable to mutations that occur very early on in development. These areas are in the initial portions of genes, where the cell tends ...