Transposon sequencing analyses reveal that among genomically diverse clinical Mycobacterium intracellulare strains and the type strain, 131 genes were comprehensively identified as universal essential ...

Humans have it. So does Drosophila. But not yeast. That "it" is a small pause at the start of gene activity—a brief molecular halt that may have helped life evolve from simple cells to complex animals ...

Analyzing stochastic cell-to-cell variability can potentially reveal causal interactions in gene regulatory networks.

A newly discovered promoter element "start" points to a shared regulatory syntax for controlling transcription initiation in bacteria, archaea, and eukaryotes.

Genomes are key to unlocking life's evolutionary history. The presence and absence of certain genetic sequences and mutations can give us clues to the order in which species diverge. However, even ...

As global temperatures rise, Cold Spring Harbor Laboratory (CSHL) scientists work to grow stronger, more resilient crops. Yet, this process is challenging. Plants often have several related genes that ...