Everyday habits such as heavy drinking and unhealthy eating can gradually damage the pancreas. Once injured, the consequences ...

The issue of cholesterol is a lot more complicated than most people think – there are as many as eight different blood tests ...

Credit: Arrowhead Pharmaceuticals. Plozasiran is an apoC-III-directed small interfering ribonucleic acid designed to reduce levels of hepatic and serum apoC-III protein, thereby increasing clearance ...

Extremely high fat levels in the blood from familial chylomicronemia syndrome (FCS) typically causes symptoms like abdominal pain and an inflamed pancreas (pancreatitis), but FCS can also affect the ...

PASADENA, Calif.--(BUSINESS WIRE)--Arrowhead Pharmaceuticals, Inc. (NASDAQ: ARWR) today announced that it has completed enrollment in SHASTA-3, SHASTA-4, and MUIR-3, the company’s global Phase 3 ...

Genetic and epidemiological evidence indicates that triglyceride-rich lipoproteins are causal risk factors for atherosclerotic cardiovascular disease (ASCVD). Elevated levels of plasma triglyceride ...

Familial hyperchylomicronemia syndrome (FCS) is a rare disorder you get from genes passed down from your parents. When you have it, your body isn’t able to break down (metabolize) fat. Specifically, ...

Familial chylomicronemia syndrome (FCS) is an autosomal recessive disorder, characterized by alterations in the catabolism of chylomicrons and by increased levels of plasma triglycerides. It has been ...

The Food and Drug Administration (FDA) has accepted for review the New Drug Application (NDA) for plozasiran for the treatment for familial chylomicronemia syndrome (FCS). In FCS, mutations in the ...

Researchers discover a new mechanism controlling the uptake of lipids from digested food. The maintenance of a balanced lipid homeostasis is critical for our health. While consumption of excessive ...