Human activities add large quantities of nitrogen to the environment, much of which gets washed into streams and rivers.

TikTok is overflowing with videos promising to “flush” uric acid, reverse gout overnight, or cure joint pain with a single ...

Organ meats offer a source of protein, B vitamins, magnesium, selenium, zinc, and iron. Liver, kidney, and heart are ...

XORTX Therapeutics Inc. (" XORTX " or the “ Company ”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat ...

Gut microbiota capable of metabolizing uric acid and purines may play a key role in reducing gout diagnoses, and although the findings from new retrospective and prospective studies suggest key roles ...

Background: Inflammatory bowel disease (IBD) is a multifactorial disorder characterized by aberrant immune activation and metabolic dysregulation. Despite significant advances in understanding immune ...

Background: The rise of antibiotic resistance underscores the urgent need for new antimicrobial agents. Nucleoside antibiotics are a structurally diverse class with broad biological activities, among ...

NUDT5 enzyme acts as a molecular scaffold that maintains metabolic balance. Inside every cell, a finely tuned metabolic network determines when to build, recycle or stop producing essential molecules.

ABSTRACT: Hepatic abscesses can develop in association with biliary disease, through hematogenous spread via the portal circulation, by continuity with an intra-abdominal infection, as a post-surgical ...

While most enzymatic activity is conducted through chemical binding interactions between molecules, in some cases, the mere presence of an enzyme can affect intracellular functions. While exploring ...

A world-first discovery, published in the journal Science, rewrites our understanding of how cells control the production of DNA’s building blocks - and how this process affects the response to widely ...

Eat a low-fat, low-purine diet with foods like nonfat milk, low-fat yogurt, and vegetables to lower uric acid. Avoid alcohol and sugary drinks, which can raise uric acid levels. Elevated levels of ...