In a recent study, people with osteoporosis had higher levels of alkaline phosphatase (ALP) in their blood compared to patients who didn’t have osteoporosis. The link was strongest in young women with ...

Hypophosphatasia (HPP) is an inherited disease caused by a low activity of tissue-nonspecific alkaline phosphatase, a hydrolase that removes phosphate groups from many molecules. Decreased alkaline ...

Common blood test results may offer an early clue to bone loss, suggesting that alkaline phosphatase levels could help identify people who may benefit from earlier osteoporosis assessment before ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. mTOR (mechanistic target of rapamycin) kinase ...

Laboratory Technical Project Manager Gianmarco Chumbe has been part of the CNET Home team since 2018. He is in charge of developing and carrying out testing procedures for a wide variety of home ...

Background: Worsening renal function (WRF) has been associated with poor outcome in the patients with acute heart failure (AHF). Recently, venous congestion had been paid attention to the important ...

Objectives Elevated baseline serum alkaline phosphatase (ALP) may correlate with higher medium-term to long-term mortality in the general population and in patients with chronic kidney disease.

Lanthanides, known for their unique coordination chemistry, can modulate enzymatic activity by interacting with active or allosteric sites. This study investigated the effects of lanthanides on ...

Introduction: We have previously demonstrated that overexpression of tissue-nonspecific alkaline phosphatase (TNAP) in endothelial cells increases vascular calcification and accelerates ...

Considering the intrinsic importance of alkaline phosphatase (ALP) as a biomarker in disease monitoring and as a mostly widely used biolabel for signal transmission in bioanalysis, the development of ...