The San Francisco 49ers' losses to the Green Bay Packers and Buffalo Bills mark the worst two-game stretch by a defending conference champion since the 1970 merger.

After sparking the 49ers with a handful of impressive runs, Christian McCaffrey looked like himself early in the game against the Buffalo Bills. On seven carries, McCaffrey rushed for 53 yards to go along with a pair of catches for 14 yards against the Bills.

Taking the field in Week 1 with sky-high expectations, what with eight-year head coach Kyle Shanahan having just taken his team to the Super Bowl last year, the 49ers lost games they should have won, lost key players at seemingly every turn, and suddenly sit at 5-6 as longshots to win the division?