San Francisco fumbled the ball three times and lost all three. Brock Purdy dropped back to pass 20 times for 86 net yards.
Following a brutal 38-10 loss to the Green Bay Packers last week, things didn't get any easier for the San Francisco 49ers ...
The Week 13 Sunday slate closes with the Buffalo Bills (9-2) hosting the San Francisco 49ers (5-6) on Sunday Night Football.
A Buffalo Bills fan seemingly tried to use the snowy weather to their advantage on Sunday night as they appeared to toss a ...
San Francisco 49ers running back Christian McCaffrey suffered a knee injury and limped to the locker room in the second ...
After games on both Thanksgiving and Black Friday, the NFL caps off the Sunday slate with the Buffalo Bills hosting the San ...
Bills on NBC's Sunday Night Football, the NFL Week 13 schedule and more. More: NFL playoff picture: Chiefs become ...
The Bills sacked Purdy twice, Greg Rousseau getting one while the other was called a team sack because Purdy lost a fumble ...