NFL Week 13 closes with Sunday Night Football as the San Francisco 49ers visit Highmark Stadium and the Buffalo Bills. Time ...

State and team officials brought all hands on deck to ensure that a massive dose of lake effect snow would not hinder Buffalo ...

Former Wisconsin running back Isaac Guerendo scored the second touchdown of his young NFL career in the San Francisco 49ers’ ...

See what Kyle Shanahan, Brock Purdy, Sean McDermott and Josh Allen had to say following the Week 13 primetime contest.

Here are your top 49ers storylines for Monday, December 2nd.

It's Buffalo Bills vs San Francisco 49ers in Week 13 of the NFL season. Can Josh Allen and company outduel Christian McCaffery and Deebo Samuel?

The Buffalo Bills easily got past the San Francisco 49ers 35-10 on a snowy Sunday Night Football matchup. Here are winners ...

Christian McCaffrey and Jordan Mason both landed on IR after the 49ers lost to the Bills in Week 13. Isaac Guerendo will now ...

The San Francisco 49ers looked out of their element as the Buffalo Bills cruised to an easy 35-10 win on Sunday Night ...

Josh Allen expertly navigated snow-topped turf, finding the end zone in a multitude of fashions and even receiving credit for ...

NFL fans are extremely passionate about there teams and one fan got a little too passionate after pushing someone down the ...

The return of a superstar may be short lived. It was a snowy night in Buffalo, New York when the San Francisco 49ers took on ...