After sparking the 49ers with a handful of impressive runs, Christian McCaffrey looked like himself early in the game against ...

On a snowy night in Orchard Park, N.Y., the Buffalo Bills clinched the AFC East title with a dominant win over the San ...

The Week 13 Sunday slate closes with the Buffalo Bills (9-2) hosting the San Francisco 49ers (5-6) on Sunday Night Football.

San Francisco 49ers running back Christian McCaffrey suffered a knee injury and limped to the locker room in the second ...

Bills on NBC's Sunday Night Football, the NFL Week 13 schedule and more. More: NFL playoff picture: Chiefs become ...

The 49ers’ third straight defeat came in 35-10 fashion to the AFC East-clinching Buffalo Bills amid a snowstorm at Highmark ...

The most recent instance of a quarterback scoring on his own pass was when Marcus Mariota had his pass batted up into the air ...

Buffalo Bills quarterback Josh Allen had fun in the snow as his team produced an offensive avalanche to blow away the San ...

The Chiefs were the first team to clinch an NFL playoff berth, but the Bills can one-up them by sealing the AFC East with a ...

The San Francisco 49ers' losses to the Green Bay Packers and Buffalo Bills mark the worst two-game stretch by a defending ...

A picturesque setting of snow was the perfect backdrop for a Buffalo Bills team that has now won its fifth straight AFC East ...

Here is where the San Francisco 49ers sit in the NFL Week 14 power rankings after a loss to the Buffalo Bills on "Sunday ...