When photos of bright blue dogs wandering through the ruins of Chernobyl began circulating online, the internet leapt to a ...

NVIDIA introduces CodonFM, an advanced RNA foundation model designed to enhance digital biology research by analyzing RNA sequences, predicting mutation effects, and optimizing mRNA design. NVIDIA has ...

2 Department of Histopathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK 3 Cambridge Liver Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK Background ...

Resarchers targeted the genetics that underpin fruit elongation in domesticated cucumbers which are longer than their stubby, bitter tasting wild relatives. Cucumbers, a summer staple of salads and ...

Engineering of adeno-associated virus (AAV) replication proteins may provide new insights into Parvoviral replication. The authors created a useful collection of Rep protein variants with changes that ...

Transfection of AAV containing a K340H mutation in Rep. (A) To evaluate the activity of Rep, a K340H mutation was generated in the genome. Residue K340 directly interfaces with ATP in the helicase ...

If SpliceAI is able to identify the impact of such variants, this would be great, because usually synonymous alterations are filtered out of variant calling tools. Setting a manual filter for SpliceAI ...

Joshua L. C. Wong, Sophia David, Julia Sanchez-Garrido, Jia Z. Woo, Wen Wen Low, Fabio Morecchiato, Tommaso Giani, Gian Maria Rossolini, Konstantinos Beis, Stephen J ...

Hi first of all thanks for this great tool! I am trying to read my .maf file but I want classify all the mutations as non-silent because I need all for oncoplot and I want to see the mutations if they ...

DNA has to be interpreted by cells. The letters or bases that make up genetic sequences are read in sets of three, and those three-base sequences are known as codons. Every codon encodes for one amino ...