A new way to map how cells choose their fate

Researchers from Kyushu University have developed an innovative computational method, called ddHodge, that can reconstruct ...

B cells temporarily regain stem-like flexibility, increasing risk of lymphoma formation

Immune cells called B cells make antibodies that fight off invading bacteria, viruses and other foreign substances. During ...
eLife

Translational reading frame determines the pathogenicity of C-terminal frameshift deletions in MeCP2: an alternative therapeutic approach

This study offers important insight into the pathogenic basis of intragenic frameshift deletions in the carboxy-terminal domain of MECP2, which account for some Rett syndrome cases, yet similar ...
Frontiers

Novel Gene and Variant Discovery in Human Genetic Disorders: From Coding and Non-Coding RNA variants

Rapid advances in sequencing technologies have transformed our ability to diagnose human genetic disorders, yet many patients still lack a molecular ...