The tricarboxylic acid cycle: Oxidation in the round

Having considered localization of respiratory functions in mitochondria and in prokaryotic cells, it's time to return to the ...
C&EN

Highly Enantioselective Hydroxylation of 3-Arylpropanenitriles to Access Chiral β-Hydroxy Nitriles by Engineering of P450pyr Monooxygenase

Key Laboratory of Biocatalysis & Chiral Drug Synthesis of Guizhou Province, Generic Drug Research Center of Guizhou Province, School of Pharmacy, Zunyi Medical University, Zunyi 563000, China Key ...
C&EN

Synthesis and Evaluation of Prodrugs of α-Carboxy Nucleoside Phosphonates

School of Chemistry, Analytical and Biological Chemistry Research Facility, Synthesis and Solid State Pharmaceutical Centre, University College Cork, Cork T12 K8AF, Ireland School of Pharmacy, ...
Armed robbery in Revesby

Acid Drives Meta-C-H Bond Amination for M-Diphenylamine

Recently, Professor Fei Wang's research group at Nankai University developed an aromatic radical substitution reaction based on aniline protonation-induced polarity reversal, achieving the direct meta ...
SciELO

A novel approach for the synthesis of 5-substituted-1H-tetrazoles

A series of 5-substituted-1H-tetrazoles (RCN4H) have been synthesized by cycloaddition reaction of different aryl and alkyl nitriles with sodium azide in DMSO using CuSO4•5H2O as catalyst. A wide ...