Steric block antisense oligonucleotides can treat neurological diseases via the cerebrospinal fluid (CSF) route. Here, the authors demonstrate that cholesterol conjugated PMO/RNA heteroduplexes ...
State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Science, Fuzhou, Fujian 350002, China Article Views are the COUNTER-compliant ...
NMR Spectroscopy. NMR samples contained 1 mM 2- (N -morpholino) ethanesulfonic acid (MES) buffer and 2% vol/vol D 2 O, pH 6.00 ± 0.05 (14). A low concentration of MES buffer was used to reduce ...
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