ascopubs.org

Estrogen Receptor Status by Immunohistochemistry Is Superior to the Ligand-Binding Assay for Predicting Response to Adjuvant Endocrine Therapy in Breast Cancer

Immunohistochemistry (IHC) is a newer technique for assessing the estrogen receptor (ER) status of breast cancers, with the potential to overcome many of the shortcomings associated with the ...
insider.si.edu

The immunoassay handbook : theory and applications of ligand binding, ELISA, and related techniques / edited by David Wild ; associate editors, Rhys John [and others]

How to use this book / David Wild -- Immunoassay for beginners / David Wild -- Immunoassay performance measures / Chris Davies -- Principles of competitive and immunometric assays (including ELISA) / ...
Science Daily

Simplified redesign of proteins to improve ligand binding

The ability to alter proteins to refine control over binding affinity and specificity can create tailored therapeutics with reduced side effects, highly sensitive diagnostic tools, efficient ...
EurekAlert!

New proteomics method enables sensitive identification of ligand-binding proteins and their binding sites in complex system

In a study published in Nature Methods, a research group led by Prof. YE Mingliang from the Dalian Institute of Chemical Physics of the Chinese Academy of Sciences (CAS), collaborating with Prof. LUO ...
Kaleido Scope

Simplified redesign of proteins to improve ligand binding

Various approaches to such protein redesign have drawbacks. Traditional methods include time-consuming trial and error efforts, and many models in the emerging field ...