Modern Engineering Marvels on MSN
Hidden DNA weak spot near gene start mutates rapidly
These sequences are extremely prone to mutations and rank among the most functionally important regions in the entire human ...
The plausible mechanism pathway “could accelerate gene therapy/editing development,” analysts at William Blair said Thursday, while adding that additional clarity is needed. Individualized therapies ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Telomeres are essential for chromosome ...
This landmark study describes the structure of the human RAD51 filament with a recombination intermediate called the displacement loop (D-loop). Using cryogenic structural, biochemical, and ...
Natural transformation is a process in which bacteria uptake exogenous DNA from the environment during a transient physiological state called competence. The DNA can either autonomously replicate or ...
Competitive Repair by Naturally Dispersed Repetitive DNA during Non-Allelic Homologous Recombination
Genome rearrangements often result from non-allelic homologous recombination (NAHR) between repetitive DNA elements dispersed throughout the genome. Here we systematically analyze NAHR between Ty ...
Not revised: This Reviewed Preprint includes the authors’ original preprint (without revision), an eLife assessment, public reviews, and a provisional response from the authors. The paper describes ...
Transcription factors, especially FOXP1, are crucial in SCLC chemoresistance, influencing drug sensitivity and resistance pathways. FOXP1 regulates SP8 expression via its super-enhancer, impacting the ...
This cover highlights the article A regulatory module mediating temperature control of cell-cell communication facilitates tree bud dormancy release by Shashank K. Pandey, Jay Prakash Maurya, ...
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