Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...

Scientific progress depends on results that can be repeated – yet across disciplines, too many experiments fail that test. From medicine to economics, the replication crisis reveals not just flawed ...

The National Institutes of Health has updated its Strategic Plan for NIH Research to Cure Hepatitis B, a roadmap for ending the hepatitis B epidemic, focused on developing a cure as well as improved ...

Hepatitis B virus (HBV) infects more than 250 million people worldwide and can lead to chronic liver disease and liver cancer. Current antiviral therapies suppress viral replication but do not ...

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, ...

DNA, often called the blueprint of life, is built from four chemical building blocks known as deoxy-nucleoside triphosphates (dNTPs)—dATP, dTTP, dGTP, and dCTP. Cells constantly need these molecules ...

Unlock the full InfoQ experience by logging in! Stay updated with your favorite authors and topics, engage with content, and download exclusive resources. Cory Benfield discusses the evolution of ...

Amanda Kay Montoya is an Associate Professor at the University of California, Los Angeles. She serves on the Board of Directors for the Center for Open Science. She receives funding from the ...

Infectious entry of hepatitis B viruses (HBV) has nonconventional facets. Here we analyzed whether a cell-permeable peptide [translocation motif (TLM)] identified ...

I read with interest your article on the White House’s response to the replication crisis in biomedical science. You cite the Center for Open Science’s project, which couldn’t replicate 54% of ...

Chinese researchers have unveiled a remarkable breakthrough in artificial intelligence (AI): advanced systems, particularly large language models (LLMs), now possess the ability to replicate ...

ABSTRACT: Background: The Hepadnaviridae family is composed of small hepatotropic DNA viruses, divided into two main genera: Avihepadnavirus, which infects birds; and Orthohepadnavirus, which infects ...