Over-dependence on one (monopoly) or two (duopoly) players for an economically critical service exposes the economy to ...

Ultragenyx is developing setrusumab in pediatric and young adult patients across OI sub-types I, III and IV with two late-stage studies: the pivotal Phase 2/3 Orbit study and Phase 3 Cosmic study.

Setrusumab is a monoclonal antibody that inhibits sclerostin, a protein that negatively regulates bone development, allowing for new bone formation.

Neither study achieved its primary endpoint of reduction in annualized clinical fracture rate compared to placebo (ORBIT) or bisphosphonates (COSMIC) ...

For more than a decade, Julian Branch has worried about the asbestos coming out of his tap, and with good reason: where he ...

EST Ultragenyx (RARE) sinks 42% to $19.97 after osteogenesis study misses Published first on TheFly – the ultimate source for real-time, ...

Staying warm behind the wheel wasn't easy in the early 20th century, even after automakers began offering enclosed cabins.

Discover the complex backstories and overlooked strengths of 10 anime characters who are often unfairly criticized and hated ...

We located our favorite statues and asked our children to identify them and their significance. After a few minutes, they ...

The most 1980s TV commercials, with rock stars, from Michael Jackson shilling for Pepsi to Genesis hawking beer.

Tavis Malcolm, the founder of Morrison Outdoors, at his Albuquerque office in April. His company, which makes and sells ...