The pipeline of investigational therapies for hereditary angioedema (HAE) includes both novel inhibitors of known molecular targets and more ambitious gene editing-based approaches. Selected agents ...

AusperBio completes patient enrollment in phase III AUSHINE study of AHB-137 for chronic hepatitis B: San Francisco Tuesday, December 23, 2025, 15:00 Hrs [IST] AusperBio Therapeut ...

The data demonstrated that finite-duration 24-week AHB-137 monotherapy achieved a 30% functional cure rate at Week 72 (EOF) in patients with baseline HBsAg 100--1,000 IU/mL. This finding strengthens ...

Long-term prophylaxis (LTP) is the cornerstone strategy to achieve disease control and improve patient quality of life(QoL), because many patients can become virtually attack-free with an acceptable ...

In September 2025, AusperBio completed participant enrolment in two Phase II studies evaluating AHB-137 for the functional cure of CHB. "AusperBio concludes enrolment in Phase III AUSHINE trial" was ...

CAG repeats can get longer over time as the HD gene is used, like the growing potholes and cracks in an old road. New ...

POINT-HD has begun dosing its first participants with the drug RG6496, marking an early but important step for a new selective huntingtin-lowering approach.

Steric block antisense oligonucleotides can treat neurological diseases via the cerebrospinal fluid (CSF) route. Here, the authors demonstrate that cholesterol conjugated PMO/RNA heteroduplexes ...

DNA methylation involves adding a methyl group to DNA, which may influence gene expression and affect health aspects like childhood development and aging. Lifestyle factors, especially diet, may ...

DNA computing is a branch of biomolecular computing concerned with the use of DNA as a carrier of information to make arithmetic and logic operations. DNA is a transformative storage medium, but ...

Explore how the future of obesity drugs starts in preclinical discovery, addressing global challenges and advancing treatment ...

During this symposium, leading international epileptologists discussed the key challenges and opportunities that currently ...