Estrogen is known as an important hormone, and it can control many functions by regulating the activity of hundreds of genes.

Researchers have uncovered nearly 150 hidden DNA “switches” inside brain support cells that control the activity of genes ...

Maintaining CDK4/6 inhibition constrains drug‑resistant breast tumors by delaying cell‑cycle entry, and adding CDK2 inhibition further deepens control to guide post‑progression therapy.

Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy by harnessing the body's immune system to target ...

Scientists successfully extract RNA from a 130-year-old Tasmanian tiger, thylacine, revealing how its genes functioned before its extinction.

The research represents a major step forward in revealing how the three dimensional form of DNA shapes the way human biology functions. In a major step toward understanding how the physical form of ...

Scientists mapped hidden DNA switches in brain support cells to understand how gene control may influence Alzheimer’s disease ...

Researchers identify stem cell–based molecular subtypes that improve prognosis prediction in colorectal cancer and support ...

The Human Genome Project was completed a little over twenty years ago. Now, scientists involved in the 4D Nucleome Project have created a detailed map that not only showcases the human genome in 3D, ...

Scientists depicted the four-dimensional genome model to reveal how DNA folding regulates genes. The discovery helps ...

AI maps fleeting DNA quadruplexes, revealing paired structures that control genes in healthy cells and cancer.

Learn how mapping gene-control switches in an ancient sea anemone reveals how identical DNA can produce many different cell ...