The proteins of the Bcl-2 family are key players in the mitochondrial pathway of apoptosis. They form a complex interaction network that determines the permeabilization of the mitochondrial outer ...
BCL-2 family proteins are key regulators of the apoptotic pathway. Antiapoptotic members sequester the BCL-2 homology 3 (BH3) death domains of proapoptotic members such as BAX to maintain cell ...
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