In this study, researchers aimed to determine whether younger BRCA1/2 carriers who undergo oophorectomy can receive menopausal hormone therapy without increasing their risk of breast cancer.

Carriers of the BRCA1 cancer gene had a significantly increased risk of breast cancer if they used hormonal contraception (HC), pooled cohort data showed. Breast cancer risk increased by 29% in BRCA1 ...

Hormone replacement therapy (HRT) does not increase breast cancer risk in BRCA1/BRCA2 carriers, with estrogen-alone formulations showing a lower risk. The study used a matched-pair design to control ...

Previously, it was recommended for women who have a family history of breast, ovarian, tubal or peritoneal cancer to be assessed for harmful BRCA1 or BRCA2 mutations. That recommendation was last made ...

More than 1 million women have had genetic testing of BRCA1 and BRCA2, genes in which mutations can dramatically increase the risk for early-onset breast and ovarian cancer. But for many women, the ...

An affordable new BRCA gene test has hit the market, but who should take it? — -- A new genetic testing kit that hits the market today is the most affordable, and arguably one of the simplest, ...

It might feel like your world stops after receiving a diagnosis of breast or ovarian cancer. Even in that mental and emotional fog, there are several next steps to consider. Coming up with a treatment ...

When we hear about gene mutations like the BRCA gene, we think of breast cancer screening in women. But, researchers say men are also at risk for the carrying the gene, which is linked to other ...

Adding back a tiny molecule, microRNA 223-3p, to BRCA1-mutant cancer cells forces the cancer to die, researchers discovered. BRCA1-mutant cancer is the type of inherited cancer for which Angelina ...