Purdy missed the 49ers' Week 12 contest versus the Green Bay Packers last Sunday with a right shoulder injury—a game San Francisco lost 38–10. The 25-year-old was limited in practice this week on Wednesday and Thursday, and was a full participant on Friday. He's officially listed as questionable for Sunday.

San Francisco 49ers quarterback Brock Purdy is expected to return to the field on Sunday against the Buffalo Bills after recovering from a shoulder

San Francisco 49ers quarterback Brock Purdy is poised to return to action on Sunday night against the Buffalo Bills after missing a game due to a shoulder injury.

A light dusting of snow began covering the Buffalo Bills' facility on Friday as the team completed its final practice of the week inside Highmark Stadium.

The San Francisco 49ers may end up getting lucky and avoiding the worst of a snowstorm that’s hitting Buffalo this weekend ahead of Sunday night’s matchup against the Bills. A “lake effect” storm is hitting the Buffalo area starting Friday night,

ORCHARD PARK - The forecasting models are showing that Sunday night, the fabulous fall we have enjoyed in Western New York could be coming to an end, just in time for the Buffalo Bills to host the San Francisco 49ers at Highmark Stadium.

The Buffalo Bills came soaring into their bye week during NFL Week 13 riding a six-game winning streak to a 9-2 record. They are preparing to host the 5-6 San Francisco 49ers for Sunday Night Football,

The Buffalo Bills had a week off to rest after their victory over the Kansas City Chiefs in Week 11. The bye week came at a great time for Buffalo, riding high after that victory over the Chiefs pushed their win streak to six games.