Gastric cancer cells can activate KRAS-driven signals, enabling autonomous tumor growth by producing their own WNT proteins. New research reveals how gastric cancer cells exploit WNT signaling for ...

Researchers from the Ottawa HospitalResearch Institute and the University of Ottawa in Canada, along with researchers from the Centre for Genomic Regulation at the Barcelona Institute for Science and ...

The four helices conserved across the Lipocone superfamily constitute a cone-like structure, with the helices tending to coalesce on one end and open out into a pocket on the other, lined by the ...

Researchers at The Ottawa Hospital and the University of Ottawa have discovered an 18-digit code that allows proteins to attach themselves to exosomes - tiny pinched-off pieces of cells that travel ...

Researchers have identified that Dishevelled doesn't only function in the cytoplasm and at the cell membrane – it must also pass into the nucleus. A study published today in Journal of Biology reveals ...

Organoids are 3D structures made up of cells that replicate the structure and function of tissues and organs. Organoids can be derived from stem cells or tissue-specific progenitor cells. A stem cell ...

In the animal kingdom, specific growth factors control body axis development. They are produced by a small group of cells at one end of the embryo to be distributed in a graded fashion toward the ...

The muscle transmembrane protein Vangl2 helps organize the development and maintenance of connections between muscles and motor neurons, a study concludes. A skeletal muscle isn’t much use without a ...