In a paper published in PNAS, Whitehead provides structural guidance on the design of lipid nanoparticles for safe use during pregnancy. Lipid nanoparticles are the delivery vehicles that bring mRNA ...
Lipid nanoparticles (LNPs) have enormous potential for the delivery of genomic medicine. One obstacle, however, is the lack of effective ways to target specific cell types. In order to target lung ...
Product Performance – potency and dosing: Cryogenic transmission electron microscopy (Cryo-TEM) revealed more uniform, solid-core particles. Increased lipid and RNA concentrations can enhance in vivo ...
LNPs consist of ionizable lipids, which are critical for encapsulating RNA and enabling cellular uptake. Helper lipids contribute to the structural integrity and fusion with cell membranes.
A review maps high throughput strategies that link automation, microfluidics, and barcoding into a unified pipeline, enabling faster, more predictive lipid nanoparticle development for genetic ...
Within tumors in the human body, there are immune cells (macrophages) capable of fighting cancer, but they have been unable ...
University of Pennsylvania School of Engineering and Applied Science engineers say they have modified lipid nanoparticles (LNPs) to not only cross the blood-brain barrier (BBB) but also to target ...
Cayman's LipidLaunch™ research-ready LNPs, reagent kits, and screening sets help researchers pursue lipid nanoparticles (LNPs) for the delivery of nucleic acid therapies. LipidLaunch™ Research Tools ...
CHARLOTTESVILLE, Va.--(BUSINESS WIRE)--VION Biosciences, a life science platform company focused on specialty reagents in the life science research, diagnostic, and drug discovery space, announced the ...
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