Proteins that are no longer needed, defective, or potentially harmful are labeled with a molecular "tag" and dismantled in ...

A research group led by Professor Michael Glickman, dean of Technion's Faculty of Biology, has uncovered a key mechanism in ...

A mechanism responsible for breaking down toxic proteins that are involved in Alzheimer's may actually spread them to ...

Israel Institute of Technology have uncovered a surprising mechanism that may help explain how Alzheimer’s disease spreads through the brain. A cellular system designed to protect neurons by removing ...

Degradation of a protein by the ubiquitin–proteasome system (UPS) is a multistep process catalyzed by sequential reactions. Initially, ubiquitin is conjugated to the substrate in a process mediated by ...

Chains of ubiquitin proteins play key roles in cellular chemistry, including directing unwanted proteins to the proteasome for disposal. That function is carried out by a type of ubiquitin chain ...

While some viruses burst out of a host cell after shredding it open, others depart in a more genteel fashion. They assemble at the plasma membrane and, form lollipop-shaped protuberances. Then each ...

A new paper published in Nature Communications presents research on unique peptides with anti-cancer potential. The research was led by Professor Ashraf Brik and post-doctoral fellows Dr. Ganga B.