UroToday

EAU 2026: How to Read a Genetic Report for Clinical Practice?

(UroToday.com) The 2026 European Association of Urology (EAU) annual meeting featured a PARP inhibitors for prostate cancer session and a presentation by Dr. Himisha Beltran discussing how to read a ...
News Medical

Highly sensitive CRISPR-based method designed to detect low-frequency cancer mutations

Liquid biopsy is increasingly recognized as a promising tool for cancer detection and treatment monitoring, yet its effectiveness is often limited by the extremely low levels of tumor-derived DNA ...
Nature

MOE Key Laboratory of Early Prevention and Treatment for Regional High Frequency Tumor, Guangxi Medical University

MOE Key Laboratory of Early Prevention and Treatment for Regional High Frequency Tumor, Guangxi Medical University has the following research output in the current window (1 December 2024 - 30 ...
Morningstar

Korea University Researchers Develop Ultrasensitive Method to Detect Low-Frequency Cancer Mutations

SEOUL, South Korea, Dec. 9, 2025 /PRNewswire/ -- MUTE-Seq is a new liquid-biopsy method powered by an engineered ultra-precise CRISPR enzyme, FnCas9-AF2, which can distinguish single-base mismatches ...
ascopubs.org

Frequency and Heritability of WT1 Mutations in Nonsyndromic Wilms' Tumor Patients: A UK Children’s Cancer Study Group Study

Constitutional WT1 mutations occur with a low frequency (2.1%; 95% CI, 0.8% to 4.6%) in nonsyndromic WT patients. Most mutations occurred in children with unilateral WT without associated ...
ascopubs.org

Association of circulating tumor DNA (ctDNA) variant allelic frequency (VAF) with outcomes on matched targeted therapies (TT) in advanced non-small cell lung cancer (aNSCLC).

Osimertinib plus anlotinib in patients with untreated, EGFR-mutated, advanced non-small-cell lung cancer with concurrent gene alterations: A single-arm, prospective, multicenter phase II study. Safety ...