Cancer is a complex process involving a multi-faceted evolutionary process occurring at the cellular level within organisms. It is triggered by the second law of thermodynamics (disorder increases in ...
Saccharomyces cerevisiae telomeres consist of ∼350 base pairs of the sequence C 1–3 A/TG 1–3. As in most eukaryotes, yeast telomeric DNA is elongated by telomerase, a specialized reverse transcriptase ...
Scientists have for the first time mapped telomerase, an enzyme which has a kind of rejuvenating effect on normal cell aging. The findings are a step forward in the fight against cancer. In ...
Researchers at Arizona State University’s (ASU) School of Molecular Sciences and the Biodesign Institute’s Center for the Mechanism of Evolution have discovered an unprecedented pathway producing ...
Research has recently uncovered a crucial step in the telomerase enzyme catalytic cycle. This catalytic cycle determines the ability of the human telomerase enzyme to synthesize DNA. Research from the ...
Premature aging can be reversed by reactivating an enzyme that protects the tips of chromosomes, a study in mice suggests. Mice engineered to lack the enzyme, called telomerase, become prematurely ...
Sometimes stories that start with pond scum can have good endings. In the case of the single-celled organism called Tetrahymena thermophila, important bits of DNA at the ends of its chromosomes led to ...
Telomeres – which are the DNA repeats that form the tips of chromosomes and are produced by the telomerase enzyme – play a crucial, and curious, role in the life of the cell. While chromosomes are ...
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Identification of proteins that regulate telomerase may impact aging and cancer research
A study by Children's Medical Research Institute (CMRI) researchers reveals a new group of proteins that guide the powerful enzyme telomerase, opening potential doors to novel treatments for cancer, ...
Some debate whether aging is in itself a disease. However, there is no doubt that by addressing it, one can prevent, delay, and even avoid age-related diseases such as cancer, pulmonary fibrosis, ...
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