Researchers from Kyushu University have developed an innovative computational method, called ddHodge, that can reconstruct ...

New method ASPEN accurately maps gene activity from each parent in individual cells, overcoming noise in data. It revealed ...

Eight years ago, 10x Genomics launched the first commercially available single-cell RNA sequencing (scRNA-seq) product for the company’s flagship instrument, the 10x Chromium. (This occurred one year ...

RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical translation of diagnostic RNA-seq has not been widely achieved. Researchers at ...

RNA sequencing (RNA-seq) is a powerful tool in diagnosing Mendelian disorders, but the optimized sequencing depth for this technology has not yet been determined. In a new study published in the ...

Human disease is complex and influenced by a wide range of genomic variants. Sequencing accuracy is paramount in order to detect this vast array of genomic dysfunction. In genomic and multiomic ...

In the realm of modern medicine, RNA-based therapies have emerged as a promising avenue, with significant advancements in metabolic diseases, oncology, and preventive vaccines. A recent article ...