Deep learning methods have been used to augment existing energy-based physical models in 'do novo' or from-scratch computational protein design, resulting in a 10-fold increase in success rates ...

The sensor design problem Creating a protein sensor for small molecules is very difficult. The protein must first bind to the small molecule, then signal its presence. The team solved both problems ...

Protein engineering is a powerful biotechnological process that focuses on creating new enzymes or proteins and improving the functions of existing ones by manipulating their natural macromolecular ...

BOT or NOT? This special series explores the evolving relationship between humans and machines, examining the ways that robots, artificial intelligence and automation are impacting our work and lives.

A biochemist at the University of Washington School of Medicine has won the Nobel Prize in Chemistry for his groundbreaking work in computational protein design. When David Baker first set out decades ...

Three scientists were named winners of the 2024 Nobel Prize in Chemistry for their innovations in the fields of computational protein design and structure prediction. One half of the prize was awarded ...

On Wednesday, the Nobel Committee announced that it had awarded the Nobel Prize in chemistry to researchers who pioneered major breakthroughs in computational chemistry. These include two researchers ...

Proteins are biology’s molecular machines. They’re our bodies’ construction workers—making muscle, bone, and brain; regulators—keeping systems in check; and local internet—responsible for the ...

Proteins designed by artificial intelligence (AI) are being considered for use in treating everything from snakebites to cancer. A Nature Communications paper, out this week, describes how Australian ...

A research team has developed a next-generation anti-inflammatory protein using AI and supercomputing. The team, led by ...