Biophysicists have elucidated why unexpected structures can sometimes arise during protein design. Artificially designed proteins are usually based on building blocks that obey strict rules of ...
An international research team led by a Korean scientist has succeeded in designing large-scale protein structures that ...
We outline protein interaction networks for 13 ion channels isolated from mouse hearts and show that several protein components are shared between ion channel networks. Multi-omic data integration ...
How large, fully folded proteins can pass through cell membranes without destroying them has long been one of the open questions in cell biology. Using cryo-electron microscopy (cryo-EM), Leonid ...
An international research team led by a Korean scientist has succeeded in designing large-scale protein structures that ...
Nitrogenases are two-component metalloenzymes, consisting of a reductase component, or Fe protein that provides electrons through a [4Fe:4S] cluster and is the site of ATP hydrolysis, and the actual ...
Artificially designed proteins are usually based on building blocks that obey strict rules of symmetry. As such, their structure can generally be predicted using computer simulations. But there are ...