Detecting cancer in the earliest stages could dramatically reduce cancer deaths because cancers are usually easier to treat when caught early.

Of all our organ systems, the gastrointestinal tract contains the highest levels of endogenous and exogenous proteases (also known as proteinases and peptidases); however, our understanding of their ...

Transcriptomic and proteomic technologies are generating a wealth of data that are frequently used by scientists to predict the function of proteins based on their expression or presence. However, ...

The blood test achieved high accuracy, with 98% specificity and 73% sensitivity for detecting pancreatic cancer. When combined with CA 19-9 biomarker testing, the sensitivity increased to 85% while ...

As efforts to find effective antivirals to combat the SARS-CoV-2-caused COVID-19 pandemic continue, a new study explores the viral enzyme PLpro, encoded in the nonstructural protein nsp3, and its ...

A new blood test could help doctors detect pancreatic cancer earlier, potentially improving survival rates for one of the deadliest cancers. A new blood test could help doctors detect pancreatic ...

Rhomboid proteases are evolutionary conserved intramembrane serine proteases. Because of their emerging role in many important biological pathways, rhomboids are potential drug targets. Unfortunately, ...

Brensocatib has demonstrated efficacy in reducing neutrophil serine protease activity and symptom burden in non-cystic fibrosis bronchiectasis. GLP-1 inhibitors show potential in managing obstructive ...