Researchers at Zhejiang University School of Medicine have identified a single point mutation in the normal PML gene that can block the effect of arsenic trioxide, a frontline drug for acute ...

This transcript has been edited for clarity. Gail J. Roboz, MD: Hi, everyone. My name is Dr Gail Roboz, and welcome to Medscape InDiscussion. Today, we're going to be talking about acute myeloid ...

Acute promyelocytic leukaemia (APL) is a distinct subtype of acute myeloid leukaemia driven by the PML-RARA fusion oncoprotein, which blocks differentiation of myeloid precursors at the promyelocyte ...

Children with acute promyelocytic leukemia (APL) treated with all-trans retinoic acid (ATRA) plus arsenic trioxide -- without maintenance therapy -- were able to achieve outcomes similar to the ...

APOLLO: Optimizing the Treatment of High-Risk Acute Promyelocytic Leukemia With All-Trans Retinoic Acid and Arsenic Trioxide While Minimizing the Role of Chemotherapy The following represents ...

Carlo Acutis, the first Roman Catholic saint of the millennial generation, was in the right place at the wrong time. Carlo Acutis When he developed the rare, aggressive blood cancer called acute ...

A Houston hematologist said that decades ago, before a reliable treatment was discovered, a diagnosis of Acute Promyelocytic Leukemia (APL) often was akin to a death sentence. Patients nowadays can be ...

Jaguars defensive end Josh Hines-Allen said his seven-year-old son, Wesley, is in remission after fighting acute ...

Please provide your email address to receive an email when new articles are posted on . Bixby and colleagues conducted a phone survey of 120 randomly selected hospitals across the U.S. to assess the ...

Incidence of acute leukemia in pregnancy is extremely low, symptoms overlap with gestation, and delayed diagnosis amplifies the need for coordinated hematology–maternal-fetal management. A 23-patient ...