There are cells in the body known as pluripotent stem cells that are yet to specialize in a particular biological function. These cells maintain the potential to become any of the possible cell types ...

Monitoring certain proteins secreted in human pluripotent stem cell (hPSC) culture provides a fast, non-invasive way to identify changes in human stem cells’ pluripotency, thus overcoming a major ...

A new study has found that L1td1, a protein evolutionarily co-opted from the Long interspersed nuclear element 1 (LINE1) retrotransposon, functions as a critical "gatekeeper" restricting pluripotent ...

A new super-resolution system microscopy can assess the pluripotency and differentiation of live stem cells, spearheading a new era in stem-cell research and systems biology. This technology can help ...

Partially or fully differentiated cells can acquire, or be reprogrammed for, stem cell-like pluripotency, according to two studies published this week. The research adds to a growing body of work on ...

Scientists have identified a key component of cellular reprogramming that may aid in more efficiently creating induced pluripotent stem (iPS) cells, according to a study published online in Nature ...

Figure 1. The schematic illustrates the mechanisms governing pluripotency exit, highlighting the pivotal role of PIAS4. By stabilizing KDM5B through SUMOylation, PIAS4 cooperatively modulates H3K4me3 ...

Differentiation of pluripotent stem cells (PSCs) is regulated through a methionine-mediated mechanism, which has now been pinpointed by researchers. They have revealed that zinc (Zn) plays a crucial ...

There are cells in the body known as pluripotent stem cells that are yet to specialize in a particular biological function. These cells maintain the potential to become any of the possible cell types ...

Researchers report insights into the mechanism of how human NANOG facilitates the activation of cell pluripotency. There are cells in the body known as pluripotent stem cells that are yet to ...