This is a preview. Log in through your library . Abstract BACE1 is the rate-limiting enzyme for amyloid-β peptides (Aβ) generation, a key event in the pathogenesis of Alzheimer’s disease (AD). By an ...
Shanghai Institute of Organic Chemistry has described oleanamide derivatives acting as Kelch-like ECH-associated protein 1 (KEAP1)/nuclear factor erythroid 2-related factor 2 (NFE2-related factor 2; ...
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Euphorbia neriifolia L. extract protects against cardiomyocyte injury and heart failure
Announcing a new publication for Acta Materia Medica journal. Heart failure (HF) remains a major global health challenge with ...
Vividion announces publication on discovery and preclinical study of small molecules activating KEAP1 via a covalent molecular glue to degrade NRF2.
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