The assay has a clinically relevant five-day turnaround time and can be conducted on as little as 20 ng genomic DNA with a batch size of up to forty samples in a single run. Assay performance with ...

Conclusion: The multiplex assay identifies colon cancers with MSI-H by assessing three highly accurate microsatellite markers. This assay identifies a smaller MSI-H cohort with more homogeneous ...

Dr. Samantha Lewis will discuss the value of MSI as a biomarker and techniques to measure microsatellite instability. She will then describe the development of a new PCR assay to detect MSI in solid ...

Mice and rats are a fundamental component of drug discovery research. Standard outbred stocks and inbred strains of rodents are used extensively for drug safety and pharmacokinetic testing. Our ...

Microsatellite instability (MSI) is a hypermutation phenotype that results from impaired DNA mismatch repair (MMR). The presence of high levels of MSI (MSI-H) is potentially predictive of Lynch ...

Researchers from Johns Hopkins University have shown that a new panel of long mononucleotide repeats (LMR) might offer advantages over traditional microsatellite instability (MSI) detection methods in ...

The new Droplet Digital PCR Microsatellite Instability (MSI) RUO assay can be completed in one day on a ddPCR-based platform to quantify the level of MSI present in colorectal tumors. Using either a ...

Understanding population genetic structure provides insight into the evolutionary past, present, and future of a species. In this study, we examine the rangewide population genetic structure of the ...

Bio-Rad Laboratories, Inc. (CA, USA) recently launched its ddPCR Microsatellite Instability (MSI) Assay, which detects instability in the genome that makes people susceptible to colorectal cancer and ...