Oocytes are immature egg cells that develop in almost all female mammals before birth. The propagation of future generations depends on this finite reserve of cells surviving for many years without ...

Mechanistic model for MTOC maturation in GV oocytes. The MTOC (grey) activates near the oocyte cortex, which requires recruitment of CKAP5 and TACC3. After activation, MTOC migrates to the nuclear ...

Communication between oocytes and granulosa cells is essential for oocyte formation, dormancy, reawakening, and maturation. Researchers have demonstrated that a protein complex called the exocyst ...

Researchers have found that a carefully orchestrated act of X-chromosome 'yoyo' predicts the successful and efficient development of mammalian egg cells. The findings could pave the way for generating ...

The new method offers researchers a powerful new platform to investigate the molecular mechanisms that control oogenesis, the process by which egg cells develop, and lays important groundwork for ...

Understand the role of reproductive biotech in overcoming biological limits in fertility treatments and enhancing success ...