Product Performance – potency and dosing: Cryogenic transmission electron microscopy (Cryo-TEM) revealed more uniform, solid-core particles. Increased lipid and RNA concentrations can enhance in vivo ...

ITHACA, N.Y. – A new material developed at Cornell University could significantly improve the delivery and effectiveness of mRNA vaccines by replacing a commonly used ingredient that may trigger ...

Engineers have modified lipid nanoparticles (LNPs) -- the revolutionary technology behind the COVID-19 mRNA vaccines -- to not only cross the blood-brain barrier (BBB) but also to target specific ...

Just as a chef perfects a dish by experimenting with flavors and textures, the researchers used an iterative process, testing variations to find the ideal structure for the ionizable lipid. This lipid ...

Key presentation unveiled Acuitas’ Next-Generation LNP Advancements, which is designed to enhance potency and safety, expand delivery beyond the liver, and enable broader therapeutic impact Additional ...

When formulating mRNA into lipid nanoparticles (LNP), various copy numbers of mRNA are encapsulated, leading to a distribution of mRNA loading levels within the LNPs. It is unclear whether the mRNA ...

Every winter, Austin gets walloped by cedar fever: runny noses, scratchy throats, watering eyes, and canceled plans as ...

Örn Almarsson is the Co-Founder and CEO of a startup biopharma company called Axelyf (Hafnarfjörður, Iceland & MA, USA) that is developing lipid technologies to safely and efficiently deliver mRNA ...

A new material could significantly improve the delivery and effectiveness of mRNA vaccines by replacing a commonly used ingredient that may trigger unwanted immune responses in some people. (Nanowerk ...