Obesity associated with hypothalamic dysfunction was initially described in patients with craniopharyngioma. Hypothalamic obesity may also result from brain radiation, infection (eg, tuberculosis), ...

Hypothalamic obesity (HyOb) develops when brain damage or conditions like Prader-Willi syndrome disrupt the hypothalamus, impairing hunger and energy regulation. Traditional calorie-based weight-loss ...

Metabolic syndrome (MetS) is a multifaceted disorder that impacts approximately 20–25% of the global population. This syndrome encompasses a range of conditions, including obesity, type 2 diabetes ...

This is due to epigenetic components: microRNA, histone and DNA methylation, gene mutations that alter the expression and production of the neurotrophic factor BDNF, which interacts with the receptors ...

Please provide your email address to receive an email when new articles are posted on . The FDA approved an expanded indication for setmelanotide for acquired hypothalamic obesity. The drug conferred ...