Now, in a perspective published in Nature Biotechnology, Di Carlo and colleagues from UCLA, USC and Caltech are calling on ...

An unprecedented international effort to decode how cells manage the transport of chemical substances has culminated in four studies published in Molecular Systems Biology. Led by Giulio Superti-Furga ...

Multicellular life depends on remarkable acts of cooperation. Every cell in the human body must sense what is happening ...

Many human diseases are the result of early developmental defects. As most paediatric diseases and disorders are rare, children are critically underrepresented in research. Functional genomics studies ...

Thanks to increasingly efficient and affordable gene sequencing technologies, we can now chart our genetic blueprint in unprecedented detail. But what does each gene do? Of the roughly 20,000 genes ...

A team of UK-based researchers is going where no scientist has dared to go—writing artificial human DNA from scratch. They’re hoping the project will answer fundamental questions about the human ...

AN ADULT HUMAN body consists of some 37trn cells. Not so long ago, these were thought to come in 220 different types. That number, the product of painstaking decades spent peering through microscopes ...

In a recent perspective article published in the journal Nature Communications, over 30 scientists from around the world discussed the action plans and principles of the global scientific initiative ...

The goal of the Human Liver Cell Atlas (HLiCA) is to create a comprehensive map that defines the normal functions of diverse liver cell types and their spatial relationships over the human lifespan.

Researchers with the global Human Cell Atlas (HCA) consortium report significant progress in their quest for a better understanding of the cells of the human body in health and disease, with the ...

Single-cell RNA-seq (scRNA-seq) has spent the past decade maturing into a foundational technology. Over that time, the technology has both laid the foundation for building cell atlases and allowed ...

The most complex engineering of human cell lines ever has been achieved by scientists, revealing that our genomes are more resilient to significant structural changes than was previously thought. The ...